TIGIT as an emerging immune checkpoint
H Harjunpää, C Guillerey - Clinical & Experimental Immunology, 2020 - academic.oup.com
… may protect against various solid and haematological cancers. Several monoclonal antibodies
(mAbs) that block … , targeting these pathways have the potential to induce irAEs, which are …
(mAbs) that block … , targeting these pathways have the potential to induce irAEs, which are …
Advances in targeting co‐inhibitory and co‐stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy
… this, researchers used agonistic monoclonal antibodies directed at … The clinical benefits of
anti-CD2 mAb could be seen in … can result in autoimmune cardiomyopathy, consistent with its …
anti-CD2 mAb could be seen in … can result in autoimmune cardiomyopathy, consistent with its …
[HTML][HTML] Biomaterial-enhanced treg cell immunotherapy: A promising approach for transplant medicine and autoimmune disease treatment
… to prevent allograft rejection, while autoimmune disorders lack definitive … , induces the
conversion of circulatory T cells into Tregs. (B) Functionalized biomaterials equipped with anti-CD2/…
conversion of circulatory T cells into Tregs. (B) Functionalized biomaterials equipped with anti-CD2/…
[HTML][HTML] The role of co-stimulatory molecules in chagas disease
BF Pinto, NI Medeiros, TCM Fontes-Cal, IM Naziazeno… - Cells, 2018 - mdpi.com
… Heart failure caused by chronic Chagas cardiomyopathy has … cells stimulated with anti-CD2
monoclonal antibodies have shown a … can induce Th17 cells in experimental autoimmune …
monoclonal antibodies have shown a … can induce Th17 cells in experimental autoimmune …
Targeting the Immunoproteasome in Health and Disease
S Mundt - 2016 - kops.uni-konstanz.de
… -55-induced EAE after active and passive immunization and was sufficient to prevent disease
… Moreover, during coxsackievirius B3 (CVB3)-induced myocarditis LMP7-/- mice developed …
… Moreover, during coxsackievirius B3 (CVB3)-induced myocarditis LMP7-/- mice developed …
[HTML][HTML] C3d regulates immune checkpoint blockade and enhances antitumor immunity
… to reverse or even to prevent tumor growth. C3d enhances … after culture on anti-CD3– and
anti-CD2–coated plates. Boxes in … CR2 potentiate each other in inducing tumor regression, we …
anti-CD2–coated plates. Boxes in … CR2 potentiate each other in inducing tumor regression, we …
[PDF][PDF] Targeting the Immunoproteasome in Health and
S Mundt - kops.uni-konstanz.de
… -55-induced EAE after active and passive immunization and was sufficient to prevent disease
… Moreover, during coxsackievirius B3 (CVB3)-induced myocarditis LMP7-/- mice developed …
… Moreover, during coxsackievirius B3 (CVB3)-induced myocarditis LMP7-/- mice developed …
RE-ENGINEERING THE MICROENVIRONMENT OF MICE THYMUS TO PROMOTE TOLERANCE TO A VCA TRANSPLANT
J Wang - 2019 - jscholarship.library.jhu.edu
… Induction of mixed chimerism includes but not limited to the use of cyclophosphamide, anti-CD2
… CTLA4-Ig together with anti-CD40L monoclonal antibody is recognized as one form of …
… CTLA4-Ig together with anti-CD40L monoclonal antibody is recognized as one form of …
Principles of Protein Recognition by Small T-Cell Adhesion Proteins and Costimulatory Receptors
S Ikemizu, SJ Davis - Structural Biology in Immunology, 2018 - Elsevier
… The advent of monoclonal antibodies in the mid-1970s3, 4 … presence of certain combinations
of anti-CD2 antibodies, 29 albeit in … rigid, implied that induced conformational changes were …
of anti-CD2 antibodies, 29 albeit in … rigid, implied that induced conformational changes were …
[PDF][PDF] TESIS DOCTORAL TESIS DOCTORAL
PL Gómez - 2017 - core.ac.uk
… As result, we described for the first time the capacity of anti-CD69 monoclonal antibodies (mAbs)
to induce a rapid and massive egress of mature leukocytes as well as hematopoietic …
to induce a rapid and massive egress of mature leukocytes as well as hematopoietic …